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Directing T-cell immune responses for cancer vaccination and immunotherapy. Peter Lawrence Smith * Katarzyna Piadel and Angus George Dalgleish

Abstract: Cancer vaccination and Immunotherapy has revolutionised the treatment of cancer, a result of decades of research into the immune system in health and disease. However, despite recent breakthroughs in treating otherwise terminal cancer only a minority of patients respond to cancer immunotherapy and some cancers are largely refractive to…

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